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Histone deacetylase 2
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Histone deacetylase 2 : ウィキペディア英語版
Histone deacetylase 2

Histone deacetylase 2 is an enzyme that in humans is encoded by the ''HDAC2'' gene.
== Function ==

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3066 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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